Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597563 | 0.88 | TDP1 (0.42) | OPRD1OPRK1OPRM1SLC7A5TDP1 | |
| SCHEMBL3108023 | 0.88 | TDP1 (0.42) | OPRD1OPRK1OPRM1SLC7A5TDP1 | |
| SCHEMBL2999347 | 0.88 | TDP1 (0.42) | OPRD1OPRK1OPRM1SLC7A5TDP1 | |
| SCHEMBL13315214 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL29395464 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL21652462 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL189879 | 0.87 | TDP1 (0.39) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL8957471 | 0.86 | CA1 (0.38) | OPRD1OPRK1OPRM1CA2CA1 | |
| SCHEMBL19807012 | 0.85 | COPS5 (0.38) | TDP1EYA2APPACEKDM4E | |
| SCHEMBL24627002 | 0.84 | CA1 (0.40) | TDP1EYA2APPACECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149041-B2 | Process for the preparation of gadolinium complex of (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanedioic acid disodium (Gadoxetate disodium) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-10-19 | — | — | US | disclosed |
| US-20200123178-A1 | Novel Process for the Preparation of Gadolinium Complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-Tris(Carboxylatomethyl)-3,6,9-Triazaundecanedioic Acid Disodium (Gadoxetate Disodium) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2020-04-23 | — | — | US | disclosed |
| US-5693309-A | Substituted complexing agents, complexes, and complex salts, processes for their production, and pharmaceuticals containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5482700-A | Substituted polyamino, polycarboxy complexing agent dimers for MRI and X-ray contrast | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149041-B2 | Process for the preparation of gadolinium complex of (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanedioic acid disodium (Gadoxetate disodium) | CA9, CA4, GLRX3 | OPRD1 2524/4885OPRK1 2873/4885OPRM1 2139/4885 |
| US-20200123178-A1 | Novel Process for the Preparation of Gadolinium Complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-Tris(Carboxylatomethyl)-3,6,9-Triazaundecanedioic Acid Disodium (Gadoxetate Disodium) | GLRX3, CA9, CA4 | OPRD1 2734/4885OPRK1 3179/4885OPRM1 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.