Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843187 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDSCN2ALMNA | |
| SCHEMBL6155607 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDSCN2ALMNA | |
| SCHEMBL6154464 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDSCN2ALMNA | |
| SCHEMBL6155246 | 0.76 | EPHX2 (0.37) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL6155342 | 0.76 | EPHX2 (0.36) | ALDH1A1KDM4EHPGDGAATP53 | |
| SCHEMBL8843056 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4EHPGDSCN2AGAA | |
| SCHEMBL8922314 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EHPGDSCN2ALMNA | |
| SCHEMBL8843129 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL6155386 | 0.71 | EPHX2 (0.36) | ALDH1A1KDM4EHPGDGAATP53 | |
| SCHEMBL6155633 | 0.71 | EPHX2 (0.37) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686495-A | Substituted hydrazinedicarboximidamides and methods of use thereof | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-11-11 | — | — | US | disclosed |