SCHEMBL8842365

SCHEMBL8842365

COc1ccc(S(=O)(=O)N(CCC(C)C)CC(O)C(Cc2ccccc2)NC(=O)C(C)C(C)(C)C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SPPL2A Q8TCT8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119249 1.00 SPPL2A (0.49) SPPL2A
SCHEMBL9122456 0.94 SPPL2A (0.55) SPPL2A
SCHEMBL8842520 0.94 SPPL2A (0.55) SPPL2A
SCHEMBL9123183 0.92 SPPL2A (0.49) SPPL2A
SCHEMBL9122536 0.92 SPPL2A (0.53) SPPL2A
SCHEMBL9121380 0.90 SPPL2A (0.48) SPPL2A
SCHEMBL7526248 0.89 SPPL2A (0.51) SPPL2A
SCHEMBL6099197 0.86 MLNR (0.47)
SCHEMBL5397301 0.86 MLNR (0.47) SPPL2A
SCHEMBL9123764 0.86 SPPL2A (0.56) SPPL2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0656886-B1 N-(ALKANOYLAMINO-2-HYDROXYPROPYL)-SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS SEARLE & CO (US) 1997-06-25 EP claimed