Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804866 | 0.92 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL6099960 | 0.92 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL1804868 | 0.92 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL1804867 | 0.92 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL7684686 | 0.91 | SPPL2A (0.52) | SPPL2A | |
| SCHEMBL3860333 | 0.91 | SPPL2A (0.52) | SPPL2A | |
| SCHEMBL7313847 | 0.91 | SPPL2A (0.52) | SPPL2A | |
| SCHEMBL4162274 | 0.90 | CTSD (0.51) | — | |
| SCHEMBL8842365 | 0.89 | SPPL2A (0.49) | SPPL2A | |
| SCHEMBL9119249 | 0.89 | SPPL2A (0.49) | SPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810209-B1 | Alpha - and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | SEARLE & CO (US) | 2002-06-05 | — | — | EP | claimed |
| EP-2654791-A1 | METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING HIV PROTEASE INHIBITORS | The Feinstein Institute for Medical Research (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088305-A1 | METHODS FOR TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING HIV PROTEASE INHIBITORS | THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (US) | 2012-06-28 | — | — | WO | disclosed |