Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 9/20 | 0.58 |
| ▸ | PNP | P00491 | 9/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8050655 | 0.95 | HPRT1 (0.63) | HPRT1PNP | |
| Water SCHEMBL11469150 | 0.95 | HPRT1 (0.56) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL146427 | 0.93 | HPRT1 (0.61) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL11730994 | 0.90 | HPRT1 (0.60) | HPRT1PNPUSP2TSHREDNRA | |
| Phosphoric Acid SCHEMBL11308939 | 0.88 | HPRT1 (0.65) | HPRT1PNPUSP2TSHREDNRA | |
| Phosphoric Acid SCHEMBL6439956 | 0.88 | HPRT1 (0.65) | HPRT1PNPUSP2TSHREDNRA | |
| SCHEMBL8149575 | 0.87 | HPRT1 (0.60) | HPRT1PNPUSP2TSHREDNRA | |
| Phosphoric Acid SCHEMBL11310331 | 0.87 | HPRT1 (0.64) | HPRT1PNPUSP2TSHREDNRA | |
| Phosphoric Acid SCHEMBL11327667 | 0.87 | HPRT1 (0.64) | HPRT1PNPUSP2TSHREDNRA | |
| Phosphoric Acid SCHEMBL11313332 | 0.87 | HPRT1 (0.64) | HPRT1PNPUSP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | claimed |
| US-5612348-A | Method of treating warts | RIVERS, JASON, M.D. (CA) | 1997-03-18 | — | — | US | disclosed |
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4287188-A | PARTICULARLY 9-(2-HYDROXYETHOXYMETHYL) GUANINE MONOPHOSPHATE AND SALTS, USEFUL AS ANTIVIRIAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |