Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PDCD1LG2 | Q9BQ51 | 5/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8894710 | 0.78 | LMNA (0.56) | MAOBNISCHMAOA | |
| SCHEMBL9575182 | 0.76 | MAOB (0.69) | MAOBNISCHPTGIRKDM4E | |
| SCHEMBL29014990 | 0.74 | NPC1 (0.60) | KDM4E | |
| SCHEMBL30450715 | 0.74 | NPC1 (0.60) | KDM4E | |
| SCHEMBL13175784 | 0.74 | NISCH (0.60) | MAOBNISCHPTGIRKDM4E | |
| SCHEMBL30980862 | 0.73 | NISCH (0.55) | MAOBNISCHPDCD1LG2CD274 | |
| SCHEMBL8842460 | 0.73 | MEN1 (0.50) | KDM4E | |
| Hydrochloric Acid SCHEMBL8842474 | 0.73 | NISCH (0.64) | MAOBNISCHMAOA | |
| SCHEMBL8842604 | 0.73 | CYP1A1 (0.49) | — | |
| SCHEMBL27650161 | 0.72 | MAOB (0.49) | MAOBNISCHPDCD1LG2CD274MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686456-A | DIARYLPYRIMIDINES | THE UNIVERSITY OF NORTH CAROLINA (US) | 1997-11-11 | — | — | US | disclosed |
| US-5627184-A | BACTERICIDES OF PYRIMIDINE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-05-06 | — | — | US | disclosed |
| US-5622955-A | ADMINISTERING 2,4-BIS-/4-GUANYLPHENYL/-PYRIMIDINE OR DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-04-22 | — | — | US | disclosed |
| US-5606058-A | HAVING REDUCED SIDE EFFECTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-02-25 | — | — | US | disclosed |
| US-5521189-A | PYRIMIDINE COMPOUNDS AS ANTIPROTOZOA AGENTS | THE UNIVERSITY OF NC AT CH (US) | 1996-05-28 | — | — | US | disclosed |