SCHEMBL8842853

SCHEMBL8842853

COP(=O)(OC)[C@H](Cc1ccccc1)NC=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
EPHX1 P07099 1/20 0.53
LAP3 P28838 4/20 0.45
TSHR P16473 1/20 0.39
TACR1 P25103 1/20 0.37
PLAU P00749 3/20 0.37
PLAT P00750 3/20 0.37
PLG P00747 2/20 0.37
F2 P00734 2/20 0.37
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH7 P40394 1/20 0.37
ANPEP P15144 1/20 0.37
SLC6A4 P31645 1/20 0.36
SLC18A2 Q05940 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ACP3 P15309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8741187 1.00 TAAR1 (0.54) TAAR1MEN1KMT2AEPHX1LAP3
SCHEMBL27846959 0.79 LAP3 (0.46) MEN1KMT2ALAP3PLAUPLAT
SCHEMBL6663779 0.77 LAP3 (0.44) MEN1KMT2ALAP3TSHRPLAU
SCHEMBL8681583 0.76 PLG (0.55) LAP3PLAUPLG
SCHEMBL678300 0.76 LAP3 (0.49) TAAR1MEN1KMT2AEPHX1LAP3
SCHEMBL9668003 0.76 LAP3 (0.49) TAAR1MEN1KMT2AEPHX1LAP3
SCHEMBL677381 0.76 LAP3 (0.49) TAAR1MEN1KMT2AEPHX1LAP3
SCHEMBL13431344 0.74 LAP3 (0.54) TAAR1EPHX1LAP3ANPEPSLC6A4
SCHEMBL7440650 0.73 TAAR1 (0.61) TAAR1MEN1KMT2AEPHX1LAP3
SCHEMBL7533990 0.73 HTT (0.50) MEN1KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703263-A USEFUL AS ANTIBIOTICS AND/OR AS INTERMEDIATES IN THE PREPARATION OF PHOSPHORUS-CONTAINING ANALOGS OF PEPTIDES MONSANTO COMPANY (US) 1997-12-30 US disclosed