Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331785 | 0.89 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL7327280 | 0.88 | ITGB3 (0.32) | ITGB3ITGA2BTP53 | |
| SCHEMBL7329123 | 0.87 | HDAC3 (0.36) | ITGB3ITGA2BTP53 | |
| SCHEMBL7330303 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL7425190 | 0.86 | MEN1 (0.32) | — | |
| SCHEMBL7332009 | 0.83 | MEN1 (0.33) | ITGB3ITGA2BTP53 | |
| SCHEMBL8842967 | 0.82 | MEN1 (0.33) | TP53 | |
| SCHEMBL7328479 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BTP53 | |
| SCHEMBL7331803 | 0.81 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL7330721 | 0.81 | ITGB3 (0.36) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |