Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842990 | 0.93 | SCN9A (0.35) | SCN9ACTSK | |
| SCHEMBL7330548 | 0.90 | SCN9A (0.34) | SCN9ACTSK | |
| SCHEMBL8959459 | 0.85 | SCN9A (0.35) | SCN9ACTSK | |
| SCHEMBL8843209 | 0.83 | PPIA (0.32) | — | |
| SCHEMBL7333235 | 0.82 | SCN9A (0.38) | SCN9ACTSK | |
| SCHEMBL8843400 | 0.82 | — | — | |
| SCHEMBL7322604 | 0.81 | SCN9A (0.32) | SCN9ACTSK | |
| SCHEMBL7335928 | 0.81 | MDM2 (0.33) | SCN9ACTSK | |
| SCHEMBL7327457 | 0.78 | TPSAB1 (0.35) | SCN9A | |
| SCHEMBL7332035 | 0.78 | SCN9A (0.39) | SCN9ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |