Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | TTPA | P49638 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501769 | 0.88 | ALOX5 (0.38) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL16282031 | 0.86 | ALOX5 (0.37) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL20819447 | 0.84 | ALOX5 (0.41) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL20819448 | 0.84 | ALOX5 (0.41) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL660010 | 0.84 | — | — | |
| SCHEMBL7799058 | 0.82 | ALOX5 (0.45) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL20822166 | 0.82 | AKT1 (0.36) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL10350387 | 0.82 | ALOX5 (0.42) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL11621017 | 0.81 | ALOX5 (0.39) | ALOX5MAPTLMNAUSP2CYP2C9 | |
| SCHEMBL7797212 | 0.80 | ALOX5 (0.43) | ALOX5NR1I2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8291163-A | — | — | None | — | — | JP | disclosed |
| US-5663389-A | 3,4-Dihydro-2-iodomethyl-2,5,7,8-tetramethyl-2H-1-benzopyrans | ALFA WASSERMANN S.P.A. (IT) | 1997-09-02 | — | — | US | disclosed |
| JP-H08291163-A | 3,4-DIHYDRO-2-IODOMETHYL-2,5,7,8-TETRAMETHYL-2H-1-BENZOPYRANS | ALFA WASSERMANN SPA | 1996-11-05 | — | — | JP | disclosed |
| EP-0737681-A1 | 3,4-Dihydro-2-iodomethyl-2,5,7,8-tetramethyl-2H-1-benzopyrans | ALFA WASSERMANN S.p.A. (IT) | 1996-10-16 | — | — | EP | disclosed |