Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8843652 | 0.98 | ALDH1A1 (0.57) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL10008027 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL10011199 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1GAAL3MBTL1 | |
| SCHEMBL10849337 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL5571068 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL11280233 | 0.79 | KDM4E (0.55) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL5571058 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL7735651 | 0.78 | KDM4E (0.62) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL14228427 | 0.77 | HRH3 (0.54) | ALDH1A1KDM4ETDP1GAAPOLB | |
| SCHEMBL3380016 | 0.76 | KDM4E (0.59) | ALDH1A1KDM4ETDP1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633283-A | Method for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5552439-A | AMINOPHENOL DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0722723-A2 | Phenol derivatives for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0680755-A1 | Method for treating inflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0474403-B1 | Method of treating inflammatory bowel disease | LILLY CO ELI (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5393786-A | Administering certain phenolic compounds | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5281623-A | Administering amino substituted phenolic derivatives as antiinflammatory or antiarthritic agents | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5280046-A | Using an amide containing phenol compound | THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0500336-A1 | Composition containing certain phenol and benzamide for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0476846-A2 | Method for treating imflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0474403-A1 | Method of treating inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |