Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400430 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL48805 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL29393091 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| Acetic Acid SCHEMBL19585270 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8843077 | 0.79 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL8844061 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL12831873 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBATMNPC1 | |
| SCHEMBL15247364 | 0.76 | SMN1; SMN2 (0.80) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL21994250 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL10884039 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |