Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845324 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1 | |
| SCHEMBL8844830 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1 | |
| SCHEMBL25837743 | 0.88 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| SCHEMBL24347921 | 0.86 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL26274329 | 0.86 | TSHR (0.50) | TSHRALDH1A1TDP1 | |
| SCHEMBL9278705 | 0.84 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| SCHEMBL11313872 | 0.84 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| SCHEMBL24123703 | 0.84 | TSHR (0.48) | TSHR | |
| SCHEMBL24250484 | 0.84 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1 | |
| SCHEMBL8586618 | 0.84 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-4328163-A | Process for the preparation of secondary and tertiary 2-carboxyethyl- and carboxymethylphosphines and their salts, as well as the use thereof | CHEMISCHE WERKE HUELS, A.G. (DE) | 1982-05-04 | — | — | US | disclosed |
| US-4315867-A | NICKEL CONTAINING CATALYST | CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |
| EP-0014747-A1 | Secondary and tertiary 2-carboxyethyl and carboxymethyl phosphines and their salts, process for their preparation and their use | CHEMISCHE WERKE HÜLS AG (DE) | 1980-09-03 | — | — | EP | disclosed |