⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619019 | 0.68 | — | — | |
| SCHEMBL20841336 | 0.68 | — | — | |
| SCHEMBL5077969 | 0.68 | — | — | |
| SCHEMBL6406314 | 0.66 | — | — | |
| SCHEMBL2049551 | 0.65 | — | — | |
| SCHEMBL1034862 | 0.62 | — | — | |
| SCHEMBL3555788 | 0.62 | — | — | |
| SCHEMBL12236235 | 0.59 | — | — | |
| SCHEMBL9711531 | 0.59 | — | — | |
| SCHEMBL4739278 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616585-A | Pyridopyrazine derivatives for treating alcohol and nicotine abuse and addiction | PFIZER INC. (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0536173-B1 | PYRIDOPYRAZINE DERIVATIVES FOR TREATING SUBSTANCE ABUSE AND ADDICTION | PFIZER (US) | 1995-01-04 | — | — | EP | disclosed |
| EP-0536173-A1 | PYRIDOPYRAZINE DERIVATIVES FOR TREATING SUBSTANCE ABUSE AND ADDICTION. | PFIZER (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0380217-B1 | BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS AND ANTIDEPRESSANTS | PFIZER INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5122525-A | Bis-aza-bicyclic anxiolytic agents | PFIZER INC. (US) | 1992-06-16 | — | — | US | disclosed |
| WO-1992000074-A2 | PYRIDOPYRAZINE DERIVATIVES FOR TREATING SUBSTANCE ABUSE AND ADDICTION | PFIZER INC. (US) | 1992-01-09 | — | — | WO | disclosed |
| WO-1992000075-A1 | PYRIDOPYRAZINE DERIVATIVES FOR TREATING SUBSTANCE ABUSE AND ADDICTION | PFIZER INC. (US) | 1992-01-09 | — | — | WO | disclosed |
| EP-0380217-A1 | Bis-aza-bicyclic anxiolytic agents and antidepressants | PFIZER INC. (US) | 1990-08-01 | — | — | EP | disclosed |
| WO-1990008148-A1 | BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER INC. (US) | 1990-07-26 | — | — | WO | disclosed |
| WO-1990008144-A1 | BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER INC. (US) | 1990-07-26 | — | — | WO | disclosed |