Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.48 |
| ▸ | ATIC | P31939 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844886 | 1.00 | PTGS2 (0.77) | PTGS2PTGS1POLBCYP2D6BRD4 | |
| SCHEMBL10905386 | 0.87 | PTGS2 (0.77) | PTGS2PTGS1BRD4RPS6KA3PHLPP2 | |
| SCHEMBL10905388 | 0.87 | PTGS2 (0.77) | PTGS2PTGS1BRD4RPS6KA3PHLPP2 | |
| SCHEMBL11519640 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1POLBCYP2D6BRD4 | |
| SCHEMBL11519642 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1POLBCYP2D6BRD4 | |
| SCHEMBL4280752 | 0.84 | PTGS1 (0.74) | PTGS2PTGS1POLBCYP2D6BRD4 | |
| SCHEMBL21125070 | 0.82 | PTGS1 (0.67) | PTGS2PTGS1POLBBRD4ALDH1A1 | |
| SCHEMBL11202860 | 0.81 | PTGS1 (0.55) | PTGS2PTGS1POLBCYP2D6RPS6KA3 | |
| SCHEMBL11578943 | 0.80 | HSD17B10 (0.66) | PTGS2PTGS1POLBCYP2D6RPS6KA3 | |
| SCHEMBL11219752 | 0.80 | HSD17B10 (0.66) | PTGS2PTGS1POLBCYP2D6RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | claimed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | claimed |
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5486214-A | MONO OR DISAZO DYES, LIGNIN PEROXIDASE AND VERATRYL ALCOHOL MIXTURE FOR DEGRADATION OF DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | disclosed |