Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263387 | 0.96 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL1270314 | 0.84 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Glutamine SCHEMBL10496120 | 0.83 | KMT2A (0.59) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL103942 | 0.82 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Threonine SCHEMBL7865132 | 0.81 | PTGS1 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL15361610 | 0.80 | SLC7A5 (0.38) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Phenylalanine SCHEMBL4611578 | 0.80 | SLC7A5 (0.63) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Valine SCHEMBL16348666 | 0.80 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL1537446 | 0.79 | SLC1A3 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL9139648 | 0.79 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597708-A | GENETIC ENGINEERING; DNA SEQUENCES ENCODING PLASMODIUM PROTEIN | BURROUGHS WELLCOME COMPANY (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0154454-B1 | CLONING OF DNA FOR PROTOZOAL ANTIGENS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-07-03 | — | — | EP | disclosed |
| EP-0154454-A1 | Cloning of DNA for protozoal antigens | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |