Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16225150 | 0.87 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| SCHEMBL5520321 | 0.81 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Lysine SCHEMBL9679963 | 0.80 | GSR (0.34) | SLC7A5 | |
| Alanine SCHEMBL8845239 | 0.80 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Isoleucine SCHEMBL5162371 | 0.80 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 | |
| Lysine SCHEMBL9681205 | 0.78 | GSR (0.36) | SLC7A5 | |
| Leucine SCHEMBL7366609 | 0.78 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11768678 | 0.78 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Leucine SCHEMBL2553000 | 0.78 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8679965 | 0.78 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933193-B2 | Lantibiotics and uses thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-01-13 | — | — | US | disclosed |
| US-20110305763-A1 | LANTIBIOTICS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-12-15 | — | — | US | disclosed |