Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7211600 | 0.89 | KDM4E (0.30) | KDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29922031 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL218519 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7705066 | 0.74 | GAA (0.33) | KDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL217395 | 0.71 | PDCD1 (0.31) | — | |
| SCHEMBL1452154 | 0.71 | HTR2C (0.34) | KDM4E | |
| SCHEMBL1454121 | 0.71 | HTR2C (0.34) | KDM4E | |
| SCHEMBL8382207 | 0.70 | — | — | |
| SCHEMBL8845278 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL3691856 | 0.70 | CYP11B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696213-A | HEATING IN PRESENCE OF A CATALYST SYSTEM | EXXON CHEMICAL PATENTS INC. (US) | 1997-12-09 | — | — | US | disclosed |