Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972013 | 1.00 | DGKA (0.50) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL8845277 | 0.93 | DGKA (0.50) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL27901260 | 0.91 | DGKA (0.53) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL8844811 | 0.89 | DGKA (0.56) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL8844601 | 0.89 | DGKA (0.56) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL27972196 | 0.89 | DGKA (0.50) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL8845318 | 0.89 | DGKA (0.50) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL28224918 | 0.85 | DGKA (0.50) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL1037012 | 0.84 | DGKA (0.48) | DGKAATMNAAAALDH1A1HTR2C | |
| SCHEMBL9290907 | 0.84 | DGKA (0.48) | DGKAATMNAAAALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |