Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 7/20 | 0.43 |
| ▸ | ITPR2 | Q14571 | 3/20 | 0.42 |
| ▸ | ITPR1 | Q14643 | 3/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.38 |
| ▸ | PPIP5K2 | O43314 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073513 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL6389556 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL3078845 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL4870995 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL15134078 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL5667749 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL6388024 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL8498941 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL8844497 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL6393461 | 1.00 | ITPR3 (0.43) | ITPR3ITPR2ITPR1INPPL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693521-A | USING ACETOXYALKYL ESTER OF ADENOSINE(OR GUANOSINE)-3',5'-CYCLIC MONNOPHOSPHATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-12-02 | — | — | US | disclosed |
| WO-1994023724-A1 | MEMBRANE-PERMEANT SECOND MESSENGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-10-27 | — | — | WO | disclosed |