Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441640 | 0.92 | SMN1; SMN2 (0.37) | ALDH1A1MIFADRB2ADRB1ADRB3 | |
| SCHEMBL7697156 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CES2CES1MIFADRB2 | |
| SCHEMBL15443392 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL15443027 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL15442983 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL4787371 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL148327 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CES2CES1MIFADRB2 | |
| SCHEMBL8582637 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CES2CES1MIFADRB2 | |
| SCHEMBL634058 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CES2CES1ADRB2ADRB1 | |
| SCHEMBL2306124 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CES2CES1MIFADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |