Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443836 | 0.84 | HTT (0.52) | CYP3A4HTTMEN1THRBKMT2A | |
| SCHEMBL9229997 | 0.80 | ALDH1A1 (0.41) | TSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL16774975 | 0.80 | HTT (0.47) | TSHRCYP3A4HTTUSP2ADRB2 | |
| SCHEMBL28965774 | 0.80 | ALDH1A1 (0.41) | TSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL1157501 | 0.80 | ALDH1A1 (0.41) | TSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL24063960 | 0.79 | — | — | |
| SCHEMBL988078 | 0.79 | TSHR (0.67) | TSHRCYP3A4HTTMEN1THRB | |
| SCHEMBL8636270 | 0.79 | TSHR (0.67) | TSHRCYP3A4HTTMEN1THRB | |
| SCHEMBL1132722 | 0.79 | TSHR (0.67) | TSHRCYP3A4HTTMEN1THRB | |
| SCHEMBL1133315 | 0.79 | TSHR (0.67) | TSHRCYP3A4HTTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679539-A | Oxidized polyethylene or polypropylene particulate supports | HUDSON DEREK (US) | 1997-10-21 | — | — | US | disclosed |