Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845708 | 1.00 | MEN1 (0.42) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8914128 | 1.00 | MEN1 (0.42) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8914134 | 1.00 | MEN1 (0.42) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8845710 | 1.00 | MEN1 (0.42) | MEN1KMT2ACA12CA1CA2 | |
| Cyclopropane SCHEMBL8918515 | 0.94 | MEN1 (0.39) | MEN1KMT2ACA12CA1CA2 | |
| Cyclopropane SCHEMBL8918512 | 0.94 | MEN1 (0.39) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL8914129 | 0.86 | HTR2A (0.41) | MEN1KMT2ALMNAHTTCYP1A2 | |
| SCHEMBL8845500 | 0.86 | HTR2A (0.41) | MEN1KMT2ALMNAHTTCYP1A2 | |
| SCHEMBL8845503 | 0.86 | HTR2A (0.41) | MEN1KMT2ALMNAHTTCYP1A2 | |
| SCHEMBL8914133 | 0.86 | HTR2A (0.41) | MEN1KMT2ALMNAHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5658914-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658927-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-4879315-A | Cyclopropyl analogs as anti-estrogenic, anti-tumor and female fertility agents | THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) | 1989-11-07 | — | — | US | disclosed |