Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914133 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8845503 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8845500 | 1.00 | HTR2A (0.41) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8914128 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAHTTCYP2C19 | |
| SCHEMBL8914134 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAHTTCYP2C19 | |
| SCHEMBL8845708 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAHTTCYP2C19 | |
| SCHEMBL8845710 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAHTTCYP2C19 | |
| SCHEMBL8845720 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAHTTCYP2C19 | |
| SCHEMBL9558816 | 0.81 | CHRNA7 (0.41) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8845461 | 0.81 | MAPT (0.56) | MEN1KMT2AMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-4442119-A | Cyclopropyl analogs as estrogenic and anti-fertility agents | THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) | 1984-04-10 | — | — | US | disclosed |