Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 10/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217486 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL28493815 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL11430622 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL1697699 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL7638807 | 0.97 | — | — | |
| SCHEMBL9490928 | 0.90 | TSHR (0.38) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL7780103 | 0.88 | — | — | |
| SCHEMBL24926281 | 0.82 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL16337946 | 0.82 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL13633253 | 0.82 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-A1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | Roche Diagnostics GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015784-A2 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-30 | — | — | WO | disclosed |