Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 10/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671135 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL22624238 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL24926281 | 1.00 | TSHR (0.47) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL27562733 | 0.97 | TSHR (0.44) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL15619237 | 0.94 | FDPS (0.39) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL11803019 | 0.89 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL27561647 | 0.89 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL13712150 | 0.89 | TSHR (0.42) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL28365145 | 0.88 | LMNA (0.46) | TSHRTHRBFDPSSMPD1ALDH1A1 | |
| SCHEMBL4445523 | 0.88 | FDPS (0.39) | TSHRTHRBFDPSSMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618974-B2 | Gyrase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-17 | — | — | US | disclosed |