Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186322 | 0.95 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7181038 | 0.83 | MAPT (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| Lithium Ion SCHEMBL7175365 | 0.79 | MAPT (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7200327 | 0.75 | MAPT (0.40) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL3458525 | 0.68 | NPC1 (0.51) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7180163 | 0.68 | NPC1 (0.47) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL19185513 | 0.67 | MAPT (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7184573 | 0.67 | ELANE (0.35) | NPC1ALDH1A1 | |
| SCHEMBL17196022 | 0.65 | MAPT (0.45) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL9840784 | 0.65 | MAPT (0.50) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758240-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING A BETA-LACTAMASE INHIBITING PENEM IN COMBINATION WITH A BETA-LACTAM ANTIBIOTIC AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 1997-02-19 | — | — | EP | disclosed |