SCHEMBL8846751

SCHEMBL8846751

CCOCc1ccccc1P

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.35
IDO1 P14902 4/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ADRA1A P35348 1/20 0.32
TAAR1 Q96RJ0 3/20 0.31
ALDH1A1 P00352 3/20 0.31
TDP1 Q9NUW8 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
KDM4E B2RXH2 2/20 0.31
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
THRB P10828 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648250 0.84 IDO1 (0.39) DPP4IDO1MAPTL3MBTL1NPSR1
SCHEMBL9862096 0.78 KDM4E (0.42) DPP4IDO1TAAR1KDM4E
SCHEMBL21796063 0.77 TACR1 (0.38) DPP4IDO1MAPTL3MBTL1NPSR1
SCHEMBL8750546 0.77 L3MBTL1 (0.44) IDO1MAPTL3MBTL1NPSR1ALDH1A1
SCHEMBL8750455 0.76 TAAR1 (0.45) MAPTTAAR1ALDH1A1TDP1TP53
Hydrochloric Acid SCHEMBL20719635 0.76 IDO1 (0.39) IDO1MAPTNPSR1TAAR1ALDH1A1
SCHEMBL9419149 0.76 IDO1 (0.59) IDO1MAPTTAAR1ALDH1A1TSHR
SCHEMBL18892799 0.76 NPSR1 (0.37) DPP4IDO1MAPTL3MBTL1NPSR1
SCHEMBL1245021 0.74 IDO1 (0.57) IDO1TAAR1TSHR
Ammonia Solution, Strong SCHEMBL21518160 0.74 TAAR1 (0.43) MAPTTAAR1ALDH1A1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644206-B1 Olefin polymerization catalyst and process for preparing polyolefin SHOWA DENKO KK (JP) 1997-12-29 EP disclosed
EP-0644206-A1 Olefin polymerization catalyst and process for preparing polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-03-22 EP disclosed