Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576151 | 1.00 | FOLH1 (0.45) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL20945365 | 0.94 | FOLH1 (0.51) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL6616069 | 0.82 | FOLH1 (0.46) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL11406719 | 0.81 | FOLH1 (0.42) | FOLH1GNPATLMNACYP1A2 | |
| SCHEMBL569594 | 0.78 | FOLH1 (0.49) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL161213 | 0.78 | FOLH1 (0.49) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL161214 | 0.78 | FOLH1 (0.49) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL29396372 | 0.77 | FOLH1 (0.52) | FOLH1CPB2GSRRNPEPMMP2 | |
| Hydrochloric Acid SCHEMBL6979380 | 0.76 | FOLH1 (0.47) | FOLH1CPB2GSRRNPEPMMP2 | |
| Hydrochloric Acid SCHEMBL6979376 | 0.76 | FOLH1 (0.47) | FOLH1CPB2GSRRNPEPMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543949-B1 | ENZYMIC ALTERATION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1997-10-22 | — | — | EP | claimed |
| EP-0543949-A4 | ENZYMIC ALTERATION OF HAIR GROWTH | — | 1993-08-04 | — | — | EP | claimed |
| EP-0543949-A1 | ENZYMIC ALTERATION OF HAIR GROWTH. | HANDELMAN JOSEPH H (US) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003140-A1 | ENZYMIC ALTERATION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1992-03-05 | — | — | WO | claimed |
| EP-0198893-B1 | HAIR GROWTH MODIFICATION | HANDELMAN, Joseph H. (US) | 1992-03-04 | — | — | EP | claimed |
| EP-0198893-A4 | HAIR GROWTH MODIFICATION. | HANDELMAN JOSEPH H (US) | 1988-05-10 | — | — | EP | disclosed |
| EP-0198893-A1 | HAIR GROWTH MODIFICATION. | HANDELMAN JOSEPH H (US) | 1986-10-29 | — | — | EP | disclosed |
| WO-1986002269-A1 | HAIR GROWTH MODIFICATION | HANDELMAN, JOSEPH, H. (US) | 1986-04-24 | — | — | WO | disclosed |