Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL10577874 | 0.93 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28272567 | 0.91 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL28788428 | 0.91 | AKR1B1 (0.80) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL1011338 | 0.90 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL11697627 | 0.90 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL31633222 | 0.88 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL10595500 | 0.88 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL23649545 | 0.88 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL25287435 | 0.88 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL25293218 | 0.88 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605831-B1 | Filler-containing resin composition and stretched films using same | MITSUBISHI CHEM CORP (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5385972-A | For waterproofing films having good elastic recovery, strength and gas permeability | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0605831-A1 | Filler-containing resin composition and stretched films using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5126391-A | Ethylene copolymer with olefin or diolefin, with glyceride of hydroxy aliphatic acid additive, tear strength | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0459142-A2 | Filler-containing stretched film | MITSUBISHI CHEMICAL CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |