Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847139 | 0.84 | GRIK1 (0.46) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL8847368 | 0.82 | GRIK1 (0.47) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL8847224 | 0.81 | GRIK1 (0.43) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL379205 | 0.81 | GRIK1 (0.64) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL19483357 | 0.81 | GRIK1 (0.37) | GRIK1GRIK2HDAC1HDAC2HDAC3 | |
| SCHEMBL19483387 | 0.81 | GRIK1 (0.37) | GRIK1GRIK2HDAC1HDAC2HDAC3 | |
| SCHEMBL15442112 | 0.80 | GRIK1 (0.42) | GRIK1GRIK2 | |
| SCHEMBL7879260 | 0.78 | CHRM1 (0.46) | GRIK1GRIK2HDAC1HDAC2CHRM1 | |
| SCHEMBL3104177 | 0.77 | — | — | |
| SCHEMBL8847137 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2HDAC1HDAC2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778820-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1997-06-18 | — | — | EP | claimed |
| WO-1996006821-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1996-03-07 | — | — | WO | claimed |