Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550179 | 0.90 | GRIK1 (0.62) | GRIK1GRIK2SLC1A3SLC1A2CPA1 | |
| SCHEMBL8847113 | 0.85 | GRIK1 (0.56) | GRIK1GRIK2SLC1A3SLC1A2CPA1 | |
| SCHEMBL8847065 | 0.81 | GRIK1 (0.53) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8847092 | 0.79 | GRIK1 (0.50) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL379205 | 0.76 | GRIK1 (0.64) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8847127 | 0.76 | GRIK1 (0.50) | GRIK1GRIK2SLC1A3SLC1A2CPA1 | |
| SCHEMBL8847227 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2SLC1A3SLC1A2CPA1 | |
| SCHEMBL8847137 | 0.76 | GRIK1 (0.55) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25944727 | 0.75 | SLC1A3 (0.54) | GRIK1GRIK2SLC1A3SLC1A2CPA1 | |
| SCHEMBL8847096 | 0.75 | GRIK1 (0.46) | GRIK1GRIK2SLC1A3SLC1A2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778820-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1997-06-18 | — | — | EP | claimed |
| WO-1996006821-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1996-03-07 | — | — | WO | claimed |