SCHEMBL8847337

SCHEMBL8847337

O=S(=O)(O)c1ccnc(S(=O)(=O)O)c1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.37
CYP1A2 P05177 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HIF1A Q16665 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
NAPRT Q6XQN6 1/20 0.32
KDM4E B2RXH2 2/20 0.31
FABP3 P05413 1/20 0.31
FABP4 P15090 1/20 0.31
FABP5 Q01469 1/20 0.31
CYP2C19 P33261 1/20 0.31
PIK3C3 Q8NEB9 1/20 0.31
TTR P02766 1/20 0.31
TET2 Q6N021 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PGAM1 P18669 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30158265 1.00 COMT (0.37) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL28528905 0.75 COMT (0.48) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL2112972 0.74 COMT (0.49) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL8847279 0.74 KDM4E (0.35) COMTKDM4EFABP3FABP4FABP5
SCHEMBL29564068 0.74 COMT (0.49) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL6095568 0.74 MEN1 (0.36) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL6095575 0.74 MEN1 (0.36) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL10921837 0.70 TSHR (0.41) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL11442551 0.70 COMT (0.37) COMTCYP1A2HSD17B10HIF1AALDH1A1
SCHEMBL4991971 0.70 COMT (0.58) COMTCYP1A2HSD17B10HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101838830-B Electrolyte of electroplating palladium-nickel alloy UNIV XIAMEN 2012-08-15 CN claimed
CN-101838830-A Electrolyte of electroplating palladium-nickel alloy UNIV XIAMEN 2010-09-22 CN claimed
CN-117561271-A Cyclic cell penetrating peptides 恩特拉达治疗公司 2024-02-13 CN disclosed
CN-116212048-A Cell surface coupling of nanoparticles 麻省理工学院 2023-06-06 CN disclosed
CN-101838830-B Electrolyte of electroplating palladium-nickel alloy UNIV XIAMEN 2012-08-15 CN disclosed
CN-101838830-A Electrolyte of electroplating palladium-nickel alloy UNIV XIAMEN 2010-09-22 CN disclosed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP disclosed
US-5461126-A Process of polymerizing olefins using organonickel catalyst compositions PHILLIPS PETROLEUM COMPANY (US) 1995-10-24 US disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed
US-4745187-A Process for the preparation of water-soluble phthalocyanine dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4576755-A Water-soluble fibre-reactive phthalocyanine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed