SCHEMBL2112972

SCHEMBL2112972

O=S(=O)(O)c1cccnc1S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.49
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KMT2A Q03164 2/20 0.41
NSD2 O96028 2/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
IDE P14735 1/20 0.41
DUSP3 P51452 1/20 0.41
CCR6 P51684 1/20 0.41
BLM P54132 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPK1 P28482 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564068 1.00 COMT (0.49) COMTALDH1A1CYP1A2ALOX15HIF1A
Pyrrole SCHEMBL28107126 0.89 COMT (0.41) COMTALDH1A1CYP1A2ALOX15HIF1A
Hydrochloric Acid SCHEMBL28205807 0.81 COMT (0.50) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL4660499 0.80 COMT (0.50) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL7081072 0.78 KDM4E (0.53) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL9002773 0.78 COMT (0.49) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL7867326 0.78 COMT (0.53) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL28502273 0.78 NFE2L2 (0.43) COMTNAPRTKDM4EALOX12HTT
SCHEMBL6704751 0.77 COMT (0.47) COMTALDH1A1CYP1A2ALOX15HIF1A
SCHEMBL19043008 0.77 COMT (0.47) COMTALDH1A1CYP1A2ALOX15HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321490-A Auxiliary agent and preparation method thereof 宿迁联盛科技股份有限公司 2021-02-05 CN claimed
EP-2864380-B1 CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2017-02-01 EP claimed
US-9365452-B2 Clay-compatible additive for construction chemicals CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2016-06-14 US claimed
CN-104379622-B For the compatible additive of clay of architectural chemistry product CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2016-05-25 CN claimed
EP-2103662-B1 MULTIPLE MODIFIED DERIVATIVES OF GELATIN AND CROSSLINKED MATERIAL THEREOF BIOREGEN BIOMEDICAL CHANGZHOU (CN) 2015-11-11 EP claimed
US-20150183688-A1 CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2015-07-02 US claimed
EP-2864380-A1 CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS Construction Research & Technology GmbH (DE) 2015-04-29 EP claimed
CN-104379622-A Clay-compatible additive for construction chemicals CONSTR RES & TECH GMBH 2015-02-25 CN claimed
WO-2014001064-A1 CLAY-COMPATIBLE ADDITIVE FOR CONSTRUCTION CHEMICALS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2014-01-03 WO claimed
CN-103492881-A Assay method REACTIVLAB LTD 2014-01-01 CN claimed
US-8158754-B2 Multiple modified derivatives of gelatin and crosslinked material thereof BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2012-04-17 US claimed
US-20090306345-A1 MULTIPLE MODIFIED DERIVATIVES OF GELATIN AND CROSSLINKED MATERIAL THEREOF BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2009-12-10 US claimed
EP-2103662-A1 MULTIPLE MODIFIED DERIVATIVES OF GELATIN AND CROSSLINKED MATERIAL THEREOF Bioregen Biomedical (Changzhou) Co., Ltd. (CN) 2009-09-23 EP claimed
EP-4204381-B1 SET CONTROL COMPOSITION FOR CEMENTITIOUS SYSTEMS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2026-05-06 EP disclosed
US-12595209-B2 Mixture comprising glyoxylic acid or condensation or addition products thereof BASF SE (DE) 2026-04-07 US disclosed
EP-4511346-B1 PROCESS FOR THE PREPARATION OF A CALCIUM SILICATE HYDRATE SEED COMPOSITION USEFUL AS A HARDENING ACCELERATOR FOR CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2026-03-18 EP disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed
US-4745187-A Process for the preparation of water-soluble phthalocyanine dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4415500-A HYDROGENATION CATALYSTS ACTIVE AT INTERFACE OF AQUEOUS AND ORGANIC LIQUID PHASE; HYDROFORMYLATION YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 1983-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595209-B2 Mixture comprising glyoxylic acid or condensation or addition products thereof PLOD1, AGXT, ME1 COMT 3651/4885ALDH1A1 3654/4885CYP1A2 3834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.