SCHEMBL8847437

SCHEMBL8847437

Cc1n[c]n(-c2ccccc2)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
MAPK1 P28482 4/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
MAPT P10636 4/20 0.35
HTT P42858 4/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALOX15 P16050 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8847854 0.67 KDM4E (0.47) MEN1KMT2ASMN1; SMN2KDM4EPOLB
SCHEMBL795390 0.67 AVPR1A (0.39) MEN1KMT2ASMN1; SMN2MAPK1CYP1A2
SCHEMBL67806 0.67 HTT (0.42) KMT2ASMN1; SMN2MAPK1CYP1A2KDM4E
SCHEMBL8847661 0.66 MEN1 (0.49) MEN1KMT2AMAPK1CYP1A2CYP2C19
SCHEMBL236752 0.64 SMN1; SMN2 (0.37) MEN1KMT2ASMN1; SMN2MAPK1KDM4E
SCHEMBL7837631 0.63 KDM4E (0.42) MAPK1CYP2C19KDM4EMAPTHTT
SCHEMBL557662 0.62 CYP1A2 (0.36) MEN1KMT2ASMN1; SMN2MAPK1CYP1A2
SCHEMBL795493 0.62 MAPK1 (0.36) MEN1KMT2ASMN1; SMN2MAPK1CYP1A2
SCHEMBL416916 0.61 KDM4E (0.61) MEN1KMT2ASMN1; SMN2MAPK1CYP1A2
SCHEMBL5008016 0.60 MEN1 (1.00) MEN1KMT2AKDM4EMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
EP-4342883-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT Tosoh Corporation (JP) 2024-03-27 EP disclosed
CN-117440940-A Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element 东曹株式会社 2024-01-23 CN disclosed
CN-110997648-B Condensed ring compound 东曹株式会社 2023-12-19 CN disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-116157382-A Material for metal patterning, amine compound, electronic device, and method for forming metal pattern 东曹株式会社 2023-05-23 CN disclosed
WO-2023013615-A1 AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2023-02-09 WO disclosed
WO-2023013697-A1 MATERIAL FOR METAL PATTERNING, FLUORO COMPOUND, THIN FILM FOR METAL PATTERNING, ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2023-02-09 WO disclosed
WO-2022260096-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT 東ソー株式会社 2022-12-15 WO disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN disclosed
US-5614519-A (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists KARL THOMAE GMBH (DE) 1997-03-25 US disclosed
US-5602127-A ADMINISTERING TO TREAT HYPERTENSION KARL THOMAE GMBH (DE) 1997-02-11 US disclosed
US-5594003-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-14 US disclosed
US-5591762-A HYPOTENSIVE AGENTS DR. KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
EP-0566020-A1 Benzimidazoles, pharmaceutical compositions thereof and processes for their preparation Dr. Karl Thomae GmbH (DE) 1993-10-20 EP disclosed