SCHEMBL236752

SCHEMBL236752

[c]1nc(-c2ccccc2)c(-c2ccccc2)n1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
ALOX15 P16050 1/20 0.34
PTGS2 P35354 4/20 0.34
TSHR P16473 1/20 0.34
NSD3 Q9BZ95 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HPGD P15428 2/20 0.33
KDM4E B2RXH2 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772759 0.82 LMNA (0.38) SMN1; SMN2NPC1RAB9AALOX15TSHR
SCHEMBL1696217 0.79 MEN1 (0.41) SMN1; SMN2NPC1RAB9AALOX15PTGS2
SCHEMBL10702418 0.78 BCHE (0.40) SMN1; SMN2NPC1RAB9ABCHEHPGD
SCHEMBL7266968 0.74 NSD3 (0.42) ALOX15PTGS2TSHRNSD3CA1
SCHEMBL8848208 0.70 LMNA (0.38) SMN1; SMN2PTGS2TSHRNSD3KDM4E
SCHEMBL8848068 0.70 LMNA (0.41) PTGS2TSHRNSD3CA1CA2
SCHEMBL67806 0.68 HTT (0.42) SMN1; SMN2NPC1RAB9ATSHRHPGD
SCHEMBL27372077 0.68 NSD3 (0.55) SMN1; SMN2NPC1RAB9ANSD3MEN1
SCHEMBL8847756 0.68 MEN1 (0.42) TSHRNSD3HPGDKDM4EMEN1
SCHEMBL1168425 0.68 NPC1 (0.37) NPC1RAB9AHPGDKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845835-B2 Polymer compound having lophine structure THE UNIVERSITY OF TOKYO (JP) 2023-12-19 US claimed
US-20210238364-A1 Polymer Compound Having Lophine Structure THE UNIVERSITY OF TOKYO (JP) 2021-08-05 US claimed
CN-110028671-A The polymer and its preparation method and application of benzimidazole connection triphenylimidazolyl 湘潭大学 2019-07-19 CN claimed
CN-109988306-A The polymer and its preparation method and application of benzoxazoles connection triphenylimidazolyl 湘潭大学 2019-07-09 CN claimed
CN-106995444-B A kind of loop coil bisglyoxaline molecule, preparation method and application 华中科技大学 2019-04-23 CN claimed
CN-106905526-B Rigid backbone porous polymer and its preparation method and application with gas absorption performance 湘潭大学 2018-12-21 CN claimed
CN-107915730-A Quinacridone derivative containing nitrogen donor and its preparation method and application 浙江工业大学 2018-04-17 CN claimed
CN-107540855-A A kind of intelligent gel of light regulation and control sol-gel transformation and its application 华中科技大学 2018-01-05 CN claimed
CN-106995444-A A kind of loop coil bisglyoxaline molecule, its preparation method and application 华中科技大学 2017-08-01 CN claimed
CN-106905526-A Rigid backbone porous polymer with gas absorption performance and its preparation method and application 湘潭大学 2017-06-30 CN claimed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
EP-4342883-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT Tosoh Corporation (JP) 2024-03-27 EP disclosed
US-20240076421-A1 POLYMERIZATION PHOTOINHIBITOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-03-07 US disclosed
CN-117440940-A Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element 东曹株式会社 2024-01-23 CN disclosed
US-11851511-B2 Polymerization photoinhibitor THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-12-26 US disclosed
US-4298678-A PHOTOOXIDANT AND LEUCO DYE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-03 US disclosed
EP-0024629-A2 Photoimaging composition comprising a 2,4,5-triphenylimidazolyl dimer and at least one compound selected from the group consisting of a leuco dye and a polymerizable ethylenically unsaturated monomer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-11 EP disclosed
US-4252887-A HIGH SPEED IMAGING; PHOTOSENSITIVE TO LONGER WAVELENGTHS; USED WITH PHOTOPOLYMERIZABLE OLEFIN; OVERLAY FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-24 US disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238364-A1 Polymer Compound Having Lophine Structure TST, LTC4S, SSB SMN1; SMN2 2667/4885NPC1 2973/4885RAB9A 3482/4885
US-11845835-B2 Polymer compound having lophine structure TST, LTC4S, SSB SMN1; SMN2 2667/4885NPC1 2973/4885RAB9A 3482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.