Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | IAPP | P10997 | 2/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.53 |
| ▸ | TYR | P14679 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847587 | 1.00 | BACE1 (0.60) | BACE1APPHTTIAPPCHRNA7 | |
| SCHEMBL8848088 | 0.88 | APP (0.61) | BACE1APPHTTIAPPKDM4E | |
| SCHEMBL8848095 | 0.88 | APP (0.61) | BACE1APPHTTIAPPKDM4E | |
| SCHEMBL8965276 | 0.82 | BACE1 (0.84) | BACE1APPCHRNA7TYR | |
| SCHEMBL8965269 | 0.82 | BACE1 (0.84) | BACE1APPCHRNA7TYR | |
| SCHEMBL8756987 | 0.80 | APP (0.62) | BACE1APP | |
| SCHEMBL8756992 | 0.80 | APP (0.62) | BACE1APP | |
| SCHEMBL8756981 | 0.80 | APP (0.62) | BACE1APP | |
| SCHEMBL19358960 | 0.79 | APP (0.63) | APPTYR | |
| SCHEMBL19358961 | 0.79 | APP (0.63) | APPTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610169-A | Pharmaceutical Composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5462951-A | Dissolved in a polyoxyethylene sorbitan fatty acid ester and adsorbed onto a porosity inorganic substance | THE GREEN CROSS CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0448091-A2 | Pharmaceutical composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |