Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 10/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847941 | 1.00 | IL6ST (0.55) | IL6STSTAT3PIK3CDIDH1P2RX3 | |
| SCHEMBL31519428 | 0.88 | IL6ST (0.54) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL31519433 | 0.88 | IL6ST (0.54) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL31519430 | 0.88 | IL6ST (0.54) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL31519421 | 0.88 | IL6ST (0.54) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL8071483 | 0.85 | IL6ST (0.52) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL8071484 | 0.85 | IL6ST (0.52) | IL6STSTAT3PIK3CDIDH1FAAH | |
| SCHEMBL6432729 | 0.83 | IL6ST (0.50) | IL6STSTAT3PIK3CDIDH1NAAA | |
| SCHEMBL30984214 | 0.80 | IL6ST (0.54) | IL6STSTAT3PIK3CDIDH1P2RX3 | |
| SCHEMBL7428524 | 0.79 | IL6ST (0.50) | IL6STSTAT3PIK3CDFAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637731-A | CHOLINERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5550257-A | TREATING CENTRAL CHOLINERGIC DYSFUNCTION | AMERICAN CYANAMID COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| US-5451685-A | MANUFACTURING PHARMACEUTICALS | AMERICAN CYANAMID COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| US-5356885-A | Cholinergic agents; administering for treatment of diseases of the central nervous system | AMERICAN CYANAMID COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0510333-A1 | Substituted oxotremorine derivatives | AMERICAN CYANAMID COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |