Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847794 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8848072 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL13923722 | 0.87 | ALDH1A1 (0.45) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL14191127 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL12447238 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8847758 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL11520731 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL27646177 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL19105307 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27646206 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637731-A | CHOLINERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5550257-A | TREATING CENTRAL CHOLINERGIC DYSFUNCTION | AMERICAN CYANAMID COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| US-5451685-A | MANUFACTURING PHARMACEUTICALS | AMERICAN CYANAMID COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| US-5356885-A | Cholinergic agents; administering for treatment of diseases of the central nervous system | AMERICAN CYANAMID COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0510333-A1 | Substituted oxotremorine derivatives | AMERICAN CYANAMID COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |