Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431017 | 0.87 | LTA4H (0.50) | LTA4HBLMACE2ACACBACACA | |
| SCHEMBL31444733 | 0.85 | ACE2 (0.50) | LTA4HBLMACE2ACACBACACA | |
| SCHEMBL13062920 | 0.85 | ACE2 (0.50) | LTA4HBLMACE2ACACBACACA | |
| SCHEMBL3259070 | 0.83 | ACACB (0.69) | LTA4HBLMACE2ACACBACACA | |
| SCHEMBL16330413 | 0.83 | BLM (0.65) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL7179523 | 0.83 | BLM (0.65) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL20825612 | 0.82 | BLM (0.54) | LTA4HBLMACE2ACACBACACA | |
| SCHEMBL9001608 | 0.81 | ACE2 (0.64) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL20612872 | 0.81 | ACE2 (0.64) | LTA4HBLMACE2GABRR1CYP1A2 | |
| SCHEMBL5977939 | 0.81 | ACE2 (0.64) | LTA4HBLMACE2GABRR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621144-A | Fluorinated compounds as oxygen transport agents | ISIS INNOVATION LIMITED (GB) | 1997-04-15 | — | — | US | disclosed |
| WO-1993011098-A1 | FLUORINATED COMPOUNDS AS OXYGEN TRANSPORT AGENTS | ISIS INNOVATION LIMITED (GB) | 1993-06-10 | — | — | WO | disclosed |