SCHEMBL8848426

SCHEMBL8848426

CCOC(=O)OC(=O)OC(C)C

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.68
ALDH1A1 P00352 4/20 0.52
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
TRPA1 O75762 1/20 0.34
MMP8 P22894 1/20 0.32
MAPT P10636 1/20 0.31
HCAR2 Q8TDS4 2/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187616 0.88
SCHEMBL15259621 0.86 ALDH1A1 (0.65) SOAT1ALDH1A1LMNATSHRHSD17B10
Propane SCHEMBL22462424 0.85 TSHR (0.46) SOAT1ALDH1A1LMNATSHRHCAR2
SCHEMBL11767115 0.83 SOAT1 (0.62) SOAT1ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL288698 0.83 TSHR (0.53) SOAT1ALDH1A1LMNATSHRHSD17B10
Diethyl Pyrocarbonate SCHEMBL30366210 0.83 SOAT1 (1.00) SOAT1ALDH1A1LMNATSHRHSD17B10
Diethyl Pyrocarbonate SCHEMBL15582 0.83 SOAT1 (1.00) SOAT1ALDH1A1LMNATSHRHSD17B10
SCHEMBL11767605 0.82 ALDH1A1 (0.52) SOAT1ALDH1A1LMNATSHRHSD17B10
SCHEMBL10590813 0.82 ALDH1A1 (0.52) SOAT1ALDH1A1LMNATSHRHSD17B10
SCHEMBL8668462 0.81 SOAT1 (0.67) SOAT1ALDH1A1LMNAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100354257-C Sulfonate and a resist composition SUMITOMO CHEMICAL CO (JP) 2007-12-12 CN disclosed
CN-1576272-A Sulfonate and a resist composition SUMITOMO CHEMICAL CO (JP) 2005-02-09 CN disclosed
EP-0667851-B1 METHOD FOR PREPARING DI(ORGANO) ESTERS OF PYROCARBONIC ACID PPG INDUSTRIES INC (US) 1997-09-17 EP disclosed
EP-0667851-A1 METHOD FOR PREPARING DI(ORGANO) ESTERS OF PYROCARBONIC ACID. PPG INDUSTRIES INC (US) 1995-08-23 EP disclosed
EP-0667851-A4 METHOD FOR PREPARING DI(ORGANO) ESTERS OF PYROCARBONIC ACID. PPG INDUSTRIES INC (US) 1995-05-08 EP disclosed
WO-1994006749-A1 METHOD FOR PREPARING DI(ORGANO) ESTERS OF PYROCARBONIC ACID PPG INDUSTRIES, INC. (US) 1994-03-31 WO disclosed
US-5231211-A Polyetheramine catalysts for reaction of organohaloformates PPG INDUSTRIES, INC. (US) 1993-07-27 US disclosed
US-3985720-A Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 PPG INDUSTRIES, INC. (US) 1976-10-12 US disclosed
US-3984386-A Polymerization of ethylenically unsaturated monomer with dialkyl pyrocarbonate and hydrogen peroxide PPG INDUSTRIES, INC. (US) 1976-10-05 US disclosed