SCHEMBL8848818

SCHEMBL8848818

CCCCCCCCCCCCCCCCC(CC(C)(C)[N+](=O)[O-])C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.49
GRIK2 Q13002 2/20 0.49
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
CA2 P00918 2/20 0.46
MAPK1 P28482 1/20 0.46
GPR84 Q9NQS5 7/20 0.44
FFAR1 O14842 1/20 0.44
MAPT P10636 1/20 0.43
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
HSPD1 P10809 1/20 0.42
BLM P54132 1/20 0.42
HSPE1 P61604 1/20 0.42
ACE2 Q9BYF1 1/20 0.41
SLC1A3 P43003 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596435 0.88 CHRM1 (0.52) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL22975200 0.83 CHRM1 (0.36) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL22975199 0.83 CHRM1 (0.36) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL28632498 0.81 GRIK1 (0.59) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL19267595 0.81 GRIK1 (0.59) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL11339081 0.81 GRIK1 (0.59) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL2513155 0.79 GRIK1 (0.58) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL28074097 0.79 GRIK1 (0.58) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL28982179 0.79 CA2 (0.59) GRIK1GRIK2SLC1A2SLC1A1CA2
SCHEMBL25293689 0.76 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412606-B1 UV-stabilization of polymers using nitro compounds AKZO NOBEL NV (NL) 1997-01-15 EP disclosed
US-5122555-A Mixing with polyolefin and conventional stabilizer AKZO NV (NL) 1992-06-16 US disclosed
EP-0412606-A1 UV-stabilization of polymers using nitro compounds Akzo Nobel N.V. (NL) 1991-02-13 EP disclosed