Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685996 | 0.97 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7683580 | 0.96 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7686537 | 0.95 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL7681664 | 0.94 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7679288 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7681729 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7683696 | 0.91 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7686148 | 0.91 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL7680707 | 0.91 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL7686782 | 0.91 | AGTR1 (0.33) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643906-A | LOWERING INTRAOCULAR PRESSURE FOR TREATMENT OF GLAUCOMA | G.D. SEARLE & CO. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5441970-A | Administering angiotensin II antagonists to treat congestive heart failure or hypertension | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0579766-A1 | N-ARYLHETEROARYLALKYL IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5164403-A | Hypotensive agents, cardiovascular disorders | G. D. SEARLE & CO. (US) | 1992-11-17 | — | — | US | disclosed |
| WO-1992017469-A2 | N-ARYLHETEROARYLALKYL IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508393-A1 | N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders | G.D. Searle & Co. (US) | 1992-10-14 | — | — | EP | disclosed |