Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.33 |
| ▸ | SLC33A1 | O00400 | 3/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680753 | 0.94 | AGTR1 (0.36) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7676668 | 0.93 | SLC33A1 (0.34) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7680462 | 0.92 | AGTR1 (0.33) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7683885 | 0.92 | AGTR1 (0.34) | AGTR1AGTR2 | |
| SCHEMBL7679087 | 0.91 | AGTR1 (0.35) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7680331 | 0.91 | AGTR1 (0.36) | AGTR1AGTR2SLC33A1 | |
| SCHEMBL7682856 | 0.91 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7686765 | 0.89 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL7683779 | 0.88 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7686177 | 0.88 | SLC33A1 (0.35) | AGTR1AGTR2SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643906-A | LOWERING INTRAOCULAR PRESSURE FOR TREATMENT OF GLAUCOMA | G.D. SEARLE & CO. (US) | 1997-07-01 | — | — | US | disclosed |