Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL884927 | 0.93 | KCNA5 (0.46) | KCNA5KCNH2 | |
| SCHEMBL2063847 | 0.84 | KCNA5 (0.39) | KCNA5KCNH2 | |
| SCHEMBL2062703 | 0.77 | KCNA5 (0.74) | KCNA5KCNH2 | |
| SCHEMBL884468 | 0.76 | KCNA5 (0.79) | KCNA5KCNH2 | |
| SCHEMBL2063848 | 0.76 | KCNA5 (0.39) | KCNA5KCNH2 | |
| SCHEMBL1367453 | 0.73 | CYP3A4 (0.36) | — | |
| SCHEMBL886792 | 0.72 | KCNA5 (0.53) | KCNA5KCNH2 | |
| SCHEMBL1368340 | 0.71 | CYP11B1 (0.34) | KCNA5KCNH2 | |
| SCHEMBL884617 | 0.69 | KCNA5 (0.95) | KCNA5KCNH2 | |
| SCHEMBL1366621 | 0.68 | KCNA5 (0.31) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940406-A2 | POTASSIUM CHANNEL INHIBITORS | Merck and Co., Inc. (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007050348-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-05-03 | — | — | WO | claimed |