SCHEMBL8849449

SCHEMBL8849449

CC(=CC(=CC1CC(C)(C)NC(C)(C)C1)C(=O)O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208073 0.84 GAA (0.36) GAAALOX15POLB
SCHEMBL197543 0.84 GAA (0.36) GAAALOX15POLB
SCHEMBL27006699 0.81 GAA (0.34) GAAALOX15POLB
SCHEMBL8849245 0.79 TSHR (0.30)
SCHEMBL8849043 0.73
SCHEMBL6902521 0.70 GAA (0.43) GAAALOX15POLB
SCHEMBL2810501 0.70 ATM (0.35) GAAPOLB
SCHEMBL249444 0.70 GAA (0.43) GAAALOX15POLB
SCHEMBL918907 0.67 CD81 (0.38) GAAALOX15POLB
SCHEMBL2339142 0.66 RECQL (0.33) GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499581-B1 Stabilized polymer composition CIBA GEIGY AG (CH) 1997-07-09 EP disclosed
EP-0479725-B1 Stabilized styrene copolymers containing elastomer particles CIBA GEIGY AG (CH) 1995-04-26 EP disclosed
EP-0337431-B1 STABILIZED STYRENE COPOLYMER COMPRISING ELASTOMER PARTICLES CIBA-GEIGY AG (CH) 1993-06-23 EP disclosed
EP-0499581-A1 Stabilized polymer composition CIBA-GEIGY AG (CH) 1992-08-19 EP disclosed
EP-0479725-A2 Stabilized styrene copolymers containing elastomer particles CIBA-GEIGY AG (CH) 1992-04-08 EP disclosed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed