SCHEMBL8849600

SCHEMBL8849600

C/C(=C\CCCO[Si](C)(C)C(C)(C)C)CO

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 9/20 0.34
DUT P33316 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947094 1.00 BTN3A1 (0.34) BTN3A1DUT
SCHEMBL4345540 0.95 BTN3A1 (0.33) BTN3A1DUT
SCHEMBL4345547 0.95 BTN3A1 (0.33) BTN3A1DUT
SCHEMBL8620159 0.85 DUT (0.32) DUT
SCHEMBL8620154 0.85 DUT (0.32) DUT
SCHEMBL8207098 0.81 DUT (0.33) DUT
SCHEMBL15975343 0.79 DUT (0.34) DUT
SCHEMBL14416236 0.78 BTN3A1 (0.37) BTN3A1
SCHEMBL31399609 0.77 DUT (0.33) DUT
SCHEMBL31399585 0.77 DUT (0.33) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627192-A ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS OR ANTIOXIDANTS BRISTROL-MYERS SQUIBB COMPANY (US) 1997-05-06 US disclosed
US-5567841-A ANTICHOLESTEROL AGENT BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-22 US disclosed
US-5411969-A Antihyperlipidemic/antioxidant dihydroquinolines BRISTOL-MYERS SQUIBB COMPANY (US) 1995-05-02 US disclosed
EP-0595635-A1 Alpha-phosphorous substituted sulfonate derivatives as squalene synthetase inhibitors E.R. Squibb & Sons, Inc. (US) 1994-05-04 EP disclosed