⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240400 | 0.72 | — | — | |
| SCHEMBL11141935 | 0.68 | — | — | |
| SCHEMBL13379878 | 0.66 | — | — | |
| SCHEMBL21657360 | 0.66 | — | — | |
| SCHEMBL21657356 | 0.66 | — | — | |
| SCHEMBL22757764 | 0.65 | LMNA (0.30) | — | |
| SCHEMBL8849688 | 0.65 | — | — | |
| SCHEMBL21584269 | 0.64 | — | — | |
| SCHEMBL13379880 | 0.63 | IDH1 (0.33) | — | |
| SCHEMBL29349121 | 0.63 | IDH1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252143-C | Fluorosiloxanes aquogel | BAUSCH & LOMB (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1116326-C | Fluorosilicone hydrogels | BAUSCH & LOMB (US) | 2003-07-30 | — | — | CN | disclosed |
| CN-1273978-A | Fluorosiloxanes aquogel | BAUSCH & LOMB (US) | 2000-11-22 | — | — | CN | disclosed |
| EP-0683799-B1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5539016-A | POLYMERS FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-07-23 | — | — | US | disclosed |
| CN-1117739-A | Fluorosilicone hydrogels | BAUSCH & LOMB (US) | 1996-02-28 | — | — | CN | disclosed |
| EP-0683799-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5387662-A | For contact lenses; acrylated polysiloxanes | BAUSCH & LOMB INCORPORATED (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994018253-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5321108-A | Improving solubility of unsaturated siloxane monomers in hydrophilic monomer | BAUSCH & LOMB INCORPORATED (US) | 1994-06-14 | — | — | US | disclosed |