Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165731 | 0.86 | AHCY (0.48) | CYP1A2CYP2D6MAPK1AHCYLMNA | |
| SCHEMBL8165733 | 0.74 | CYP1A2 (0.61) | CYP1A2CYP2D6MAPK1AHCYADORA2A | |
| SCHEMBL8169226 | 0.71 | CYP1A2 (0.44) | CYP1A2CYP2D6MAPK1ADORA1 | |
| SCHEMBL12498653 | 0.69 | CYP1A2 (0.78) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL24236919 | 0.69 | CYP1A2 (0.71) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL22399280 | 0.65 | CYP1A2 (0.76) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL27943333 | 0.65 | CYP1A2 (0.76) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL14924510 | 0.63 | CYP1A2 (0.82) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL5015543 | 0.63 | CYP1A2 (0.82) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 | |
| SCHEMBL14203129 | 0.63 | CYP1A2 (0.75) | CYP1A2CYP2D6MAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766683-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC (CA) | 1997-04-09 | — | — | EP | claimed |