Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.68 |
| ▸ | RARG | P13631 | 10/20 | 0.68 |
| ▸ | RXRG | P48443 | 9/20 | 0.68 |
| ▸ | RXRB | P28702 | 8/20 | 0.68 |
| ▸ | RARA | P10276 | 3/20 | 0.68 |
| ▸ | RARB | P10826 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851049 | 1.00 | RXRA (0.68) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8159678 | 1.00 | RXRA (0.68) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8153962 | 1.00 | RXRA (0.68) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8146556 | 1.00 | RXRA (0.68) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8154273 | 0.90 | RXRA (0.71) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8154271 | 0.90 | RXRA (0.71) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8153500 | 0.90 | RXRA (0.71) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8154604 | 0.86 | RXRA (0.50) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL6049839 | 0.81 | RXRA (1.00) | RXRARARGRXRGRXRBRARA | |
| SCHEMBL8850333 | 0.81 | RXRA (1.00) | RXRARARGRXRGRXRBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800503-A1 | NOVEL TRIENOIC RETINOID COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0800503-A1 | NOVEL TRIENOIC RETINOID COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |